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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c06f736c860177d2d9c61b8f095a8f9790883b8df12153cb1b987e03cea976' 
  AND token = 'YzGd+MQa5ObxMT6UuV35AASpqG8LZSIr1BEhRv8B6SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}