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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b20a4ce55ec638947247f953ebdaf33c4ee361f4fc7f3682368593958bc116e' 
  AND token = 'RUPZ9VcmnAN4dRagYVU7uzyP+sbbyFeqA+aaW3oMVpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}