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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1219ccc7abbfbb7b8c95d226261831068eb69351789a2e4f07078b7f916b1a8a' 
  AND token = 'DmWyFRFF4q1TmCqtRSGi/JsKfhgCOrT/y1HSYomN4Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}