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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e866fffca816e3bbaa0e8c2704de7da6e31f238a468d649520cf9b17d7ba23d0' 
  AND token = 'z3DQiN5v/oBafgXUg/P4C9PIK5L3QOnswRc8cJxjxEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}