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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce21cd8f85929054680a9a821f1be033333b37e34d9f16a4b4ca5f3788055f3' 
  AND token = 'fGq3PB5BrAn44P6XTiBPUBxtllh1Bq1O/Ks4Hz7Zqno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}