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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51abeb6012d08660f26fa7eb75501faf74125b8a757b9c7eaecf7c3e43d6172' 
  AND token = '9Qs1I3cRW4wBHF+GpRksvCua23WwZ9lkqU6nqTIl3rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}