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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53140d3486b6b576a8d2f19fd75fb3b1d9da642d31d19f0884ebcff0cb6cdc9a' 
  AND token = 'L+BJuv2fAtDRq6siy6uavE1/Gv2exSZar9bHMeOGYyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}