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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed80a3d2c5ef60d8b4fd0ad6b4f216f604bc3845c83db819550c16a9d0311674' 
  AND token = 'UCqf8wblZmM/Ol+p98uD7SurBhx5W86SwdXNE8e4y8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}