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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e812f20dcaf4047f33aea533ce9656b89d524a7a314dc472198ee446a1e74aca' 
  AND token = '4y+eLiahpAIZT6jxvvrzMazD7NEoHnF7ekRbGp0eB48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}