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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373767344c9125b4b7e6f30e6fa3adc01ac87ac98c4de068b603ee4a65ead3c9' 
  AND token = 'cfqjH+DllJvbPWdCBo+q+k0WZQ6eolGb/g4+9ng3bHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}