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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ed33043715d320d98c616206b39d90016fa9d881549e86aa4777b3074de1ca' 
  AND token = 'qxb28DFfea7ddKQCj/uGQGPqoOfFcmrI51OYZIgmSnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}