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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e1a58ffeed96b1f8c4a6e2b82f11fb8811e752046964e6723b5413cea44de4' 
  AND token = 'sJTdgXXF+iYr4tpl+EDEPwmxaSlG+NUXffXxH/cMetQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}