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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3979880d10146a3893ae93a1a98034ac7527950c1420d806598453362d7bc6a2' 
  AND token = 'zTKyyPU3fiuBnUj6ReM57hf4p3LRZQniJ7lypapXwMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}