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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0ad66eb35c1f89549381b8e90db7f8803d3a71da1d66e61765650f72ed965e' 
  AND token = 'VN1xlGJT8UgSE2/rhLzsH4VMlPXXkdIg6hWcvKUSrPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}