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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10ce57c1d9f55aa0f38bb3d33b3a1cc7540b734c2278baf55664e19aaba7e40' 
  AND token = '3BqNRZMgx9e2L9pjdpCSLNRoE8CQc+NsbtmPsIxMxT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}