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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea3ed3b2190ac2d4e354f3d62affbf83e2bb02feb744cce4b12b037d991a9e50' 
  AND token = 'LIHrY/PqfNHSSeWTbICRkU0VCA8tM2ECGs3hp7UimSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}