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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f743462596853fe02e8e62bc7ca03c39d9f52d5492fecd84824a8327a7b8c23a' 
  AND token = 'HmsHaij8MFrU3TY9B6mJ4NnB6DtrQuTGREL84CaTPUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}