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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ab8d8f7f5bdf8d8a07341c830c5d7fee89e72196063d25e06ca841576d8443' 
  AND token = 'Sleu0FoyRgfLX2CwDkg1V8mNUwOZbY0DKaitct10GgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}