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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57ad3b30d669897321d9df2de8da15afff9ad48ffca6081b98a072336f17766' 
  AND token = '8sMw5vJv5XI2kPS2w355lzQr86mHmWZdB6/XErRh/DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}