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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45d1708cc70d82d273bb6d95733c8f981823f190f1b21014a9f76ccef3dcec9' 
  AND token = 'eMF56A5JCKdmrpuEgXn8h3zJkEzgICnzBJrhkQNSoHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}