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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6287e5a4925f05c6597af882a11344582dfe6e7732bd21c7f510bf450ce3db9' 
  AND token = '+9UM0J18fJaRspSAW9rBaxsHUyGyH6eqItklxFUShJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}