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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87d18b97f0bf7dce39f30b4fc8a79483dcebb144178f2275acbca83ba70e1388' 
  AND token = '50D5TR+6+xqTSsyE8NEpMejy5XNv0G04Z9B/5iMDsB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}