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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd580b12e5cd41aea4852c35ae4b84f32d6a6933ae2e9379d42e8b87f75529c94' 
  AND token = 'L+KDouk6PSufFVX1w7Smea9HhKKWc20DzVgTn8nbpr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}