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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21791c12e789002ddfde186bd1332f514286e8adc0b1b14b837c5e1e8181d2ed' 
  AND token = 'iwiMSXNeF6Rui4IVaUjckan+b3yhppVkTPTN8gJs2pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}