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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17b4539d6e08a57bb0d512530afc70f5e0da2744a6612df47a6b5e69de0b4c6' 
  AND token = 'Sq37M6+fXeAeV3uRlZXSZJaxPm/4DpnFcnbdg5cMxYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}