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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4357dd2dff2a0e5dbee540affb676d96f596400e62df2f3ecbda170cc9d29553' 
  AND token = 'aOT7hAZ5i8GiIj2zIzjf6JlrTmgeIx6tVWbwPocFqFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}