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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dafb6e57456b14e38c94e0a4e85d1386d0f2085e70cd828b79a85042b02bcbc' 
  AND token = '4fMN5MIc/ZIzq6iuK1iWomdc0Fc3OY6fnZDS1lTAE90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}