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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aab4caa602abf9e0bff1c5d12220c325b6c529ddae4ecfdeec54a65af7f1104' 
  AND token = 'dxk6N+c3MN5nmawAIezhY9VtnCTsyhjBtk+LCPPXPcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}