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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5b8c80fa7ba4184973a3b7b9cc9458d1ed212ee61a77966595c96dabcc1e52' 
  AND token = 'iZNFEs205PypYM9FWTl7u8ZYfsVolhtgulhdI4VwcTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}