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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5def9daa1f90b2b3ca78bb985ec082ad8ee6a104c30b070ce43f02dde394a9f7' 
  AND token = 'p5YGbxFtoc4dgxJNq+855oQCVApT2pas/qWtBYz+ROs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}