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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a64b4b4ba411282e2ca41cfe3735d2cddbbd737502a77e26aa546dcd698590f' 
  AND token = 'WVFO/M39hSEds1L6R9t3cv5KlUHsLON9LG+WFhluQ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}