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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e638c951dc4b8b3f25d07e27363220b9b6a1be075cafb79cbb6f818801e80bb' 
  AND token = '2FOEl9BVSQpdzWU0zk4s9pJgA0kvXdQIieo4IHLr4jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}