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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78cc0c78cc163eba45776cac3be9e38e2fba0d1fca1fd7db680da6decd8e377' 
  AND token = 'SfgzR4hYfbH44isA/bGHod0w+GO60ymQKqVIX1cd68Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}