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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b352abd6101e5e40b69fcc5cdb08028bfdfd43c508b2ef306125f6a81dbe42' 
  AND token = 'qkRpD4lOqWMCwdBCnbMl38l7K9W4YgYBOAtH1CyH3u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}