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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9248a6912c6bab9671d927fffad5068ffabc92ebdbcc60d287d6103d3f7712' 
  AND token = 'sTGlrMSdXcQS6lRSwWaVnTEkToee8cGt7729xLgv+9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}