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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e188e37fcddd4e7f3339b402a8df659d3e520e457169885c33a332e29948d3' 
  AND token = 'wxJ275Lcp7P0KPEcUmcfIpA9nOmaBMp/ymadV7ogdz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}