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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5476cc633ebb7ac876e4910f380fe3d3fab13b106b8cddef0a3cbda909262e' 
  AND token = 'R9caDPk/j/MuAUvjzSdc02QVZiPH+IgWKFC4wsdB7UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}