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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f2580cd5e66cbe37e76c36a684551ef5b509d6cfc070f54784e005b305e22f' 
  AND token = 'l561huNWDnOR5bR6im6fxGQVO1tjXASX7Ot6r4WFecw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}