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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39009f834eec0ab5ec0322c4369858ebaa65f6bad60143e73a0abf272ae66352' 
  AND token = 'dfGIbVP+QoaToeK3PinnvGBlh1jkv6C6IQGXbDsEOdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}