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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b937d1f8c69f0f737501323d6ae5a603aa1d9dbbd6e23bb45aa75b2a10652789' 
  AND token = 'k2nUI+W5Zt4R/IvCIhHTtKbNO6cAV8vXdmzANMFxXQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}