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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54b05305d349fd1469bdd518c7ddb06154a79b400b4b338f10abf46a7374963' 
  AND token = '9SDR1zwcKUKQaskJM9/K/InugNDiaZpWve17vCRPHmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}