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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f770dd33b3a1553663ca8054bc42a758af771bc8774aa1e9ef4945d8c47df9a' 
  AND token = 'lkkn2NWqE0yTFoqC7vJtqvAoI0AtEtMMoWKWxAVASkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}