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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d31efca07f659316f46e407642f61a69be39b252331d9207e516ecbad41de12' 
  AND token = 'YCgUznBF+K1LBYhQAxfHMaf/eKMXnuyivOM66qBBOnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}