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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4cbf6eefade5367df61dc799bd1d28f9468d89d76d606b6bbfb13d2a60f019' 
  AND token = '+HdR0bpetVBrU35Br71SSUuA5dyv+fg7mx3ShcEMero=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}