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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c5c1c8d9f16a30a01b749c44e75224b6041b8f76c1f49dc0cd785dc190cc2a' 
  AND token = 'puQuuP6G2ceMOj24VjfmuNxmYMmxgru4EE0tTNR7mCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}