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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c44b97637407bcd89d2bac3365ec9fc86e48acbdd82ce0cb3de9c016d9e6561a' 
  AND token = 'AS0GrlFmTQkYy2JwX2itObKpPtbqTDWTcXlK264ML1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}