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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f34246f355d4c64d855236d290b09e3dfa612866cefb635bb8dd55a6a1dfc8' 
  AND token = '5YJZJX2rVO0f23NJh7he5pcxl83/cKy/d8efxxQVinw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}