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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6128f3619850a8e149ef2214b0d3180af1fb3da914d1d2e5b8846e02996eaa5' 
  AND token = 'yvvjOyo6AW3y85wQZ0CDo7AHC3NnPWrpQjt9Qok+TGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}