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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d77d227c1a5c44b3816272503ed2eee7e99910498df329b0f375fb9876e182e' 
  AND token = '3+eXTheG6opksQnKmq7rEZmON3/AlEdSB9dUyxReqzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}