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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed5e2f4319cbfc3b9033c42bc4a077123d59a8c4ed56a68e489516d26b598b8' 
  AND token = '7QYn5PqFGjJeRcENox8bZ3+mbBY224ZDq+nlfTJXu1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}